Effect of SAIB/Solvent Ratio on Release of Methylene Blue from SABER Drops in Gelatin

This figure shows the effect of solvent content on the release of a water-soluble dye, methylene blue, from SABER into gelatin.
In the first frame, the SABER formulation is being injected into the gelatin.

  • The remaining frames show the release of the dye as a function of time.
  • The droplets contained methylene blue at 0.02 wt %.
  • Three SAIB/ethanol ratios were used (a) 90:10, (b) 70:30, (c) 50:50.
  • The release of methylene blue from the droplets is shown at 0, 1, and 4 hours.